About INCLISIRAN
Class: | PCSK9 inhibitor
Use: | Adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease to reduce LDL-C levels
Adult dose: | 284 mg administered as a subcutaneous injection once every six months after an initial dose of 284 mg at day 0 and a second dose at day 90
Pediatric dose: | Safety and efficacy have not been established in pediatric patients
Side effects: | Injection
Drug Class
PCSK9 inhibitor
Uses & Indications
Adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease to reduce LDL-C levels
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Can be stored at room temperature (up to 25°C or 77°F) for up to 30 days before use
Manufacturer & Packaging
Manufacturer: NOVARTIS EUROPHARM LIMITED, IRELAND
Package Size
1.5ml Pre-filled Syringe
Price & Supplier
Price in UAE: AED 12386.00
Dosage Information
Adult Dose
284 mg administered as a subcutaneous injection once every six months after an initial dose of 284 mg at day 0 and a second dose at day 90
Pediatric Dose
Safety and efficacy have not been established in pediatric patients
Side Effects
Injection site reactions, nausea, diarrhea, myalgia, and elevated liver enzymes
Contraindications & Precautions
Hypersensitivity to inclisiran or any component of the formulation
Important Warnings
Risk of hypersensitivity reactions; monitor liver function tests prior to initiation and periodically during treatment; not a substitute for statin therapy; use caution in patients with severe hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.