About Canagliflozin Hemihydrate
            
            Class: | SGLT2 inhibitor (sodium-glucose co-transporter 2 inhibitor)  
Use: | Management of type 2 diabetes mellitus to improve glycemic control in adults  
Adult dose: | Initial dose: 100 mg once daily before the first meal of the day; may be increased to 300 mg once daily based on individual glycemic needs and tolerability  
Pediatric dose: | Safety and efficacy not established in pediatric patients under 18 years of age  
Side effects: | Common side effects include urinary tract infections, g
         
        
            
                
                
                    
                        Drug Class
                    
                    SGLT2 inhibitor (sodium-glucose co-transporter 2 inhibitor)
                 
                
                
                    
                        Uses & Indications
                    
                    Management of type 2 diabetes mellitus to improve glycemic control in adults
                 
                
                
                    
                        Storage Requirements
                    
                    Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Janssen-Cilag S.p.A., ITALY
                    
                    
                    Package Size
                    30's (10's Blister x 3)
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 259.50
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        Initial dose: 100 mg once daily before the first meal of the day; may be increased to 300 mg once daily based on individual glycemic needs and tolerability
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients under 18 years of age
                    
                 
                
                
                    
                        Side Effects
                    
                    Common side effects include urinary tract infections, genital mycotic infections, increased urination, dehydration, and hypotension
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Contraindicated in patients with a history of serious hypersensitivity reactions to canagliflozin, severe renal impairment (eGFR < 30 mL/min), end-stage renal disease, or patients on dialysis
         
        
        
            
                Important Warnings
            
            Risk of ketoacidosis, serious urinary tract infections, and lower limb amputation; monitor renal function and assess for volume depletion before initiation and during treatment
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.