About Irinotecan
Class: | Antineoplastic agent, Topoisomerase I inhibitor
Use: | Treatment of metastatic colorectal cancer, often in combination with other chemotherapy agents; also used in small cell lung cancer.
Adult dose: | Initial dose is typically 125 mg/m² administered as an intravenous infusion over 90 minutes every 21 days, adjusted based on tolerance and side effects.
Pediatric dose: | Safety and efficacy not established; use in pediatric patients should be based on clinical judgment and specific
Drug Class
Antineoplastic agent, Topoisomerase I inhibitor
Uses & Indications
Treatment of metastatic colorectal cancer, often in combination with other chemotherapy agents; also used in small cell lung cancer.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light and moisture; do not freeze.
Manufacturer & Packaging
Manufacturer: seacross pharmaceuticals, United Kingdom
Package Size
1s
Price & Supplier
Price in UAE: AED 324.00
Dosage Information
Adult Dose
Initial dose is typically 125 mg/m² administered as an intravenous infusion over 90 minutes every 21 days, adjusted based on tolerance and side effects.
Pediatric Dose
Safety and efficacy not established; use in pediatric patients should be based on clinical judgment and specific protocols.
Side Effects
Common side effects include diarrhea, nausea, vomiting, abdominal pain, fatigue, neutropenia, and alopecia.
Contraindications & Precautions
Hypersensitivity to irinotecan or any component of the formulation; severe bone marrow suppression; diarrhea; pregnancy and lactation (unless benefits outweigh risks).
Important Warnings
Risk of severe diarrhea, which may be life-threatening; monitor for signs of dehydration; may cause myelosuppression; caution in patients with hepatic impairment; potential for secondary malignancies.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.