About Deferasirox
Class: | Iron chelator
Use: | Treatment of chronic iron overload due to blood transfusions in patients with beta-thalassemia, sickle cell disease, or other anemias; also used for non-transfusion-dependent thalassemia syndromes with significant iron overload.
Adult dose: | Initial dose is typically 10 mg/kg once daily, may be adjusted based on serum ferritin levels and tolerance, with a maximum dose of 40 mg/kg/day.
Pediatric dose: | For children aged 2 years and older, the initial dose is
Uses & Indications
Treatment of chronic iron overload due to blood transfusions in patients with beta-thalassemia, sickle cell disease, or other anemias; also used for non-transfusion-dependent thalassemia syndromes with significant iron overload.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from moisture and light.
Manufacturer & Packaging
Manufacturer: Apotex Inc., CANADA
Package Size
30's (10's Blister x 3 )
Price & Supplier
Price in UAE: AED 2186.50
Dosage Information
Adult Dose
Initial dose is typically 10 mg/kg once daily, may be adjusted based on serum ferritin levels and tolerance, with a maximum dose of 40 mg/kg/day.
Pediatric Dose
For children aged 2 years and older, the initial dose is 10 mg/kg once daily, with adjustments based on serum ferritin levels and tolerance, not exceeding 40 mg/kg/day.
Side Effects
Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), rash, elevated liver enzymes, and renal impairment.
Contraindications & Precautions
Contraindicated in patients with hypersensitivity to deferasirox or any component of the formulation, severe renal impairment (eGFR < 40 mL/min), and in patients with active hepatic disease or significant liver dysfunction.
Important Warnings
Monitor renal and hepatic function regularly during treatment; risk of gastrointestinal bleeding, skin reactions, and ocular toxicity; not recommended for use in patients with severe renal impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.