About LOMITAPIDE
Class: | Lipid-lowering agent, Microsomal triglyceride transfer protein (MTP) inhibitor
Use: | Treatment of homozygous familial hypercholesterolemia (HoFH) as an adjunct to a low-fat diet and other lipid-lowering therapies
Adult dose: | 5 mg orally once daily, may be increased to 10 mg after 2 to 4 weeks based on tolerability and response
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Gastrointestinal symptoms (nausea, diarrhea, abdominal pain
Drug Class
Lipid-lowering agent, Microsomal triglyceride transfer protein (MTP) inhibitor
Uses & Indications
Treatment of homozygous familial hypercholesterolemia (HoFH) as an adjunct to a low-fat diet and other lipid-lowering therapies
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: AMRYT PHARMACEUTICALS DAC, Ireland
Package Size
28's
Price & Supplier
Price in UAE: AED 117531.68
Dosage Information
Adult Dose
5 mg orally once daily, may be increased to 10 mg after 2 to 4 weeks based on tolerability and response
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Gastrointestinal symptoms (nausea, diarrhea, abdominal pain), liver enzyme elevations, fat-soluble vitamin deficiencies
Contraindications & Precautions
Active liver disease, pregnancy, breastfeeding, hypersensitivity to lomitapide or any component of the formulation
Important Warnings
Risk of hepatotoxicity; monitor liver function tests before and during treatment; avoid use with strong CYP3A4 inhibitors; may cause gastrointestinal side effects; ensure patients are on a low-fat diet to minimize risk of liver toxicity.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.