About Loncastuximab Tesirine-IpyI
Class: | Antibody-drug conjugate (ADC)
Use: | Treatment of adult patients with relapsed or refractory large B-cell lymphoma (LBCL) after two or more lines of systemic therapy
Adult dose: | 150 mg administered as an intravenous infusion on Day 1 of a 21-day cycle; may be adjusted based on patient response and tolerability
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in this population
Side effects: | Common side effects include fatig
Drug Class
Antibody-drug conjugate (ADC)
Uses & Indications
Treatment of adult patients with relapsed or refractory large B-cell lymphoma (LBCL) after two or more lines of systemic therapy
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; discard unused portion after 24 hours if stored at room temperature
Manufacturer & Packaging
Manufacturer: Sobi, Italy
Package Size
1's
Price & Supplier
Price in UAE: AED 85370.25
Dosage Information
Adult Dose
150 mg administered as an intravenous infusion on Day 1 of a 21-day cycle; may be adjusted based on patient response and tolerability
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in this population
Side Effects
Common side effects include fatigue, nausea, diarrhea, neutropenia, thrombocytopenia, and increased liver enzymes
Contraindications & Precautions
Hypersensitivity to loncastuximab tesirine or any component of the formulation; active infections; severe liver impairment
Important Warnings
Risk of severe infusion-related reactions; monitor patients during and after infusion; risk of myelosuppression; monitor blood counts regularly; potential for hepatotoxicity; caution in patients with hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.