About Sacituzumab govitecan hziy
Class: | Antibody-drug conjugate (ADC)
Use: | Treatment of adult patients with metastatic triple-negative breast cancer (mTNBC) who have received at least two prior therapies for metastatic disease, including a taxane and either an anthracycline or a platinum-containing chemotherapy.
Adult dose: | 10 mg/kg administered as an intravenous infusion on days 1 and 8 of a 21-day treatment cycle.
Pediatric dose: | Safety and efficacy have not been established in pediatric patients; not approved f
Drug Class
Antibody-drug conjugate (ADC)
Uses & Indications
Treatment of adult patients with metastatic triple-negative breast cancer (mTNBC) who have received at least two prior therapies for metastatic disease, including a taxane and either an anthracycline or a platinum-containing chemotherapy.
Storage Requirements
Store lyophilized powder at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. After reconstitution, the solution can be stored at 2°C to 8°C (36°F to 46°F) for up to 24 hours.
Manufacturer & Packaging
Manufacturer: Gilead Sciences INC., United States of America
Package Size
1Glass Vial
Price & Supplier
Price in UAE: AED 5281.50
Dosage Information
Adult Dose
10 mg/kg administered as an intravenous infusion on days 1 and 8 of a 21-day treatment cycle.
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; not approved for use in this population.
Side Effects
Common side effects include diarrhea, nausea, fatigue, neutropenia, anemia, vomiting, and abdominal pain.
Contraindications & Precautions
Hypersensitivity to sacituzumab govitecan-hziy or any component of the formulation; severe neutropenia (ANC < 1,000 cells/mm³) prior to treatment.
Important Warnings
Risk of severe diarrhea; monitor and manage proactively. Risk of myelosuppression; monitor complete blood counts regularly. Risk of infusion-related reactions; monitor patients during and after infusion. Use with caution in patients with hepatic impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.