About Siponimod
Class: | Sphingosine 1-phosphate receptor modulator
Use: | Treatment of relapsing forms of multiple sclerosis (MS) in adults
Adult dose: | Initial dose: 0.25 mg once daily after a 0.25 mg loading dose on the first day; maintenance dose: 0.25 mg once daily
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Headache, hypertension, liver enzyme elevation, bradycardia, infections, macular edema
Contraindications: | Hypersensitivity to siponimod or a
Drug Class
Sphingosine 1-phosphate receptor modulator
Uses & Indications
Treatment of relapsing forms of multiple sclerosis (MS) in adults
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Novartis Pharmaceuticals Corporation, U.S.A
Package Size
12s
Price & Supplier
Price in UAE: AED 990.50
Dosage Information
Adult Dose
Initial dose: 0.25 mg once daily after a 0.25 mg loading dose on the first day; maintenance dose: 0.25 mg once daily
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Headache, hypertension, liver enzyme elevation, bradycardia, infections, macular edema
Contraindications & Precautions
Hypersensitivity to siponimod or any component of the formulation; active infections; severe hepatic impairment; concurrent use of strong CYP2C9 inhibitors
Important Warnings
Risk of serious infections, including progressive multifocal leukoencephalopathy (PML); monitor liver function; may cause bradycardia; contraindicated in patients with a history of certain cardiac conditions; requires monitoring of blood pressure and heart rate during treatment initiation.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.