About Methoxy polyethylene glycol-epoetin beta (Pegzerepoitin alfa) (MIRCERA)
Class: | Erythropoiesis-stimulating agent (ESA)
Use: | Treatment of anemia associated with chronic kidney disease (CKD) in adults and pediatric patients, and for the treatment of anemia in patients with cancer receiving chemotherapy.
Adult dose: | Initial dose of 0.4 mcg/kg body weight administered once every two weeks; may be adjusted based on hemoglobin levels.
Pediatric dose: | Initial dose of 0.6 mcg/kg body weight administered once every two weeks; adjustments based on hemoglobin leve
Drug Class
Erythropoiesis-stimulating agent (ESA)
Uses & Indications
Treatment of anemia associated with chronic kidney disease (CKD) in adults and pediatric patients, and for the treatment of anemia in patients with cancer receiving chemotherapy.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: F. Hoffmann-La Roche Ltd., SWITZERLAND
Package Size
0.3ml Pre-filled Syringe
Price & Supplier
Price in UAE: AED 1302.00
Dosage Information
Adult Dose
Initial dose of 0.4 mcg/kg body weight administered once every two weeks; may be adjusted based on hemoglobin levels.
Pediatric Dose
Initial dose of 0.6 mcg/kg body weight administered once every two weeks; adjustments based on hemoglobin levels may be necessary.
Side Effects
Common side effects include hypertension, headache, arthralgia, injection site reactions, and increased risk of thromboembolic events.
Contraindications & Precautions
Hypersensitivity to methoxy polyethylene glycol-epoetin beta or any component of the formulation; uncontrolled hypertension; pure red cell aplasia (PRCA) following previous treatment with ESAs.
Important Warnings
Risk of serious cardiovascular events, including stroke and myocardial infarction, particularly in patients with pre-existing cardiovascular conditions; monitor hemoglobin levels regularly to avoid excessive increases; use caution in patients with a history of seizures.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.