About Gemtuzumab Ozogamicin
Class: | Antineoplastic agent, monoclonal antibody conjugate
Use: | Treatment of acute myeloid leukemia (AML) in adults and pediatric patients aged 2 years and older, specifically for patients with CD33-positive AML who are newly diagnosed or have relapsed.
Adult dose: | 3 mg/m² IV on days 1, 4, 7, and 10 of a 28-day cycle, with a maximum total dose of 9 mg/m² per cycle.
Pediatric dose: | 3 mg/m² IV on days 1, 4, 7, and 10 of a 28-day cycle for patients aged 2 years and older, with a maxim
Drug Class
Antineoplastic agent, monoclonal antibody conjugate
Uses & Indications
Treatment of acute myeloid leukemia (AML) in adults and pediatric patients aged 2 years and older, specifically for patients with CD33-positive AML who are newly diagnosed or have relapsed.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: Wyeth Pharmaceuticals, U.S.A
Package Size
1 Vial
Price & Supplier
Price in UAE: AED 51859.30
Dosage Information
Adult Dose
3 mg/m² IV on days 1, 4, 7, and 10 of a 28-day cycle, with a maximum total dose of 9 mg/m² per cycle.
Pediatric Dose
3 mg/m² IV on days 1, 4, 7, and 10 of a 28-day cycle for patients aged 2 years and older, with a maximum total dose of 9 mg/m² per cycle.
Side Effects
Fever, nausea, vomiting, diarrhea, fatigue, headache, infusion-related reactions, liver enzyme elevations, and myelosuppression (including thrombocytopenia, neutropenia, and anemia).
Contraindications & Precautions
Hypersensitivity to gemtuzumab ozogamicin or any component of the formulation; active hepatic disease; and patients with a history of serious infusion-related reactions.
Important Warnings
Risk of severe myelosuppression, infusion-related reactions, hepatotoxicity, and potential for tumor lysis syndrome. Monitor blood counts and liver function tests closely during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.