About Sorafenib Tosilate
Class: | Antineoplastic agent, kinase inhibitor
Use: | Treatment of advanced renal cell carcinoma (RCC), hepatocellular carcinoma (HCC), and differentiated thyroid cancer (DTC) that is refractory to radioactive iodine treatment
Adult dose: | 400 mg orally twice daily, taken on an empty stomach (at least 1 hour before or 2 hours after a meal)
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children
Side effects: | Common side effects
Drug Class
Antineoplastic agent, kinase inhibitor
Uses & Indications
Treatment of advanced renal cell carcinoma (RCC), hepatocellular carcinoma (HCC), and differentiated thyroid cancer (DTC) that is refractory to radioactive iodine treatment
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Bayer Healthcare AG, GERMANY
Package Size
60's (10's Blister x 6)
Price & Supplier
Price in UAE: AED 11450.50
Dosage Information
Adult Dose
400 mg orally twice daily, taken on an empty stomach (at least 1 hour before or 2 hours after a meal)
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children
Side Effects
Common side effects include diarrhea, hypertension, fatigue, hand-foot skin reaction, rash, nausea, and decreased appetite
Contraindications & Precautions
Hypersensitivity to sorafenib or any component of the formulation; severe hepatic impairment (Child-Pugh Class C)
Important Warnings
Risk of severe skin reactions, hypertension, gastrointestinal perforations, and bleeding; monitor liver function and blood pressure regularly; use with caution in patients with a history of cardiac disease or those receiving anticoagulants
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.