About Ritonavir
Class: | Protease Inhibitor (Antiretroviral Agent)
Use: | Ritonavir (NORVIR) is primarily used in combination with other antiretroviral agents for the treatment of HIV-1 infection.
Adult dose: | The standard adult dosing for Ritonavir as a pharmacokinetic enhancer is 100 mg to 400 mg per day, administered in one or two divided doses. When used as an antiretroviral agent, the dose is typically 600 mg twice daily, although this is less common due to its use primarily as a booster.
Pediatric dos
Drug Class
Protease Inhibitor (Antiretroviral Agent)
Uses & Indications
Ritonavir (NORVIR) is primarily used in combination with other antiretroviral agents for the treatment of HIV-1 infection.
Storage Requirements
Ritonavir tablets should be stored at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from moisture and keep in the original container.
Manufacturer & Packaging
Manufacturer: AbbVie Deutschland GmbH & Co. KG, GERMANY
Package Size
30's
Price & Supplier
Price in UAE: AED 211.63
Dosage Information
Adult Dose
The standard adult dosing for Ritonavir as a pharmacokinetic enhancer is 100 mg to 400 mg per day, administered in one or two divided doses. When used as an antiretroviral agent, the dose is typically 600 mg twice daily, although this is less common due to its use primarily as a booster.
Pediatric Dose
The pediatric dosing of Ritonavir varies based on body weight and the specific regimen. It is typically dosed at 350 mg/m² twice daily, not to exceed 600 mg twice daily. The exact dose should be determined by a healthcare provider.
Side Effects
Common side effects include nausea, vomiting, diarrhea, abdominal pain, altered taste, and increased triglycerides and cholesterol levels. Other side effects may include fatigue, headache, and rash.
Contraindications & Precautions
Ritonavir is contraindicated in patients with known hypersensitivity to ritonavir or any of its components. It should not be used with certain medications that are highly dependent on CYP3A for clearance and for which elevated plasma concentrations are associated with serious and/or life-threatening reactions.
Important Warnings
Important safety warnings include the risk of drug interactions due to its potent inhibition of CYP3A and CYP2D6 enzymes, which can lead to serious and potentially life-threatening reactions. It may also cause liver toxicity, pancreatitis, and lipid disorders. Caution is advised in patients with pre-existing liver disease, and regular monitoring of liver function tests is recommended.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.