About Mitoxantrone Hydrochloride
Class: | Antineoplastic agent, Anthracenedione
Use: | Treatment of multiple sclerosis (MS), particularly for patients with worsening relapsing forms of MS; also used in the treatment of certain types of cancer, including prostate cancer and leukemia.
Adult dose: | For MS: 12 mg/m² IV every 3 months; for cancer: 12 mg/m² IV every 21 days, adjusted based on patient tolerance and blood counts.
Pediatric dose: | Not established for pediatric use; safety and efficacy in children have not been d
Drug Class
Antineoplastic agent, Anthracenedione
Uses & Indications
Treatment of multiple sclerosis (MS), particularly for patients with worsening relapsing forms of MS; also used in the treatment of certain types of cancer, including prostate cancer and leukemia.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze.
Manufacturer & Packaging
Manufacturer: Wyeth Medica Ireland, IRELAND
Package Size
10ml Vial
Price & Supplier
Price in UAE: AED 741.50
Dosage Information
Adult Dose
For MS: 12 mg/m² IV every 3 months; for cancer: 12 mg/m² IV every 21 days, adjusted based on patient tolerance and blood counts.
Pediatric Dose
Not established for pediatric use; safety and efficacy in children have not been determined.
Side Effects
Common side effects include nausea, vomiting, hair loss, fatigue, diarrhea, and increased risk of infection due to bone marrow suppression.
Contraindications & Precautions
Hypersensitivity to mitoxantrone or any component of the formulation; pre-existing severe bone marrow suppression; pregnancy and breastfeeding; history of cardiac disease (e.g., congestive heart failure).
Important Warnings
Risk of cardiotoxicity, especially with cumulative doses; monitor cardiac function; potential for secondary malignancies; patients should be monitored for signs of infection and blood count abnormalities.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.