Octocog alfa (Coagulation Factor VIII) (KOVALTRY) – Uses, Dosage & Brands in UAE

About Octocog alfa (Coagulation Factor VIII)

Class: | Antihemophilic Factor (Recombinant), Coagulation Factor VIII Use: | KOVALTRY is used for the treatment and prophylaxis of bleeding in patients with hemophilia A (congenital Factor VIII deficiency). It is indicated for routine prophylaxis to reduce the frequency of bleeding episodes, on-demand treatment and control of bleeding episodes, and perioperative management of bleeding. Adult dose: | The dosage and duration of treatment depend on the severity of Factor VIII deficiency, the loca

Drug Class

Antihemophilic Factor (Recombinant), Coagulation Factor VIII

Uses & Indications

KOVALTRY is used for the treatment and prophylaxis of bleeding in patients with hemophilia A (congenital Factor VIII deficiency). It is indicated for routine prophylaxis to reduce the frequency of bleeding episodes, on-demand treatment and control of bleeding episodes, and perioperative management of bleeding.

Storage Requirements

Store KOVALTRY in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. It can be kept at room temperature (up to 25°C or 77°F) for a single period of up to 12 months. Once stored at room temperature, do not return to the refrigerator.

Manufacturer & Packaging

Manufacturer: Bayer AG, GERMANY

Package Size

1 Glass vial with Powder (lyophilisate) + 1 prefilled Glass syringe (3ml) with water for Injection (2.5ml solvent) + 1 vial adapter -filter + Venipuncture set with filter

Price & Supplier

Price in UAE: AED 2576.00

Dosage Information

Adult Dose

The dosage and duration of treatment depend on the severity of Factor VIII deficiency, the location and extent of bleeding, and the patient's clinical condition. For on-demand treatment, the dose is calculated based on the desired Factor VIII increase. Routine prophylaxis typically involves 20-40 IU/kg administered 2 to 3 times per week.

Pediatric Dose

Similar to adults, the dosage for pediatric patients is individualized based on the same factors. Routine prophylaxis for children may involve 20-50 IU/kg administered 2 to 3 times per week.

Side Effects

Common side effects include headache, pyrexia (fever), and infusion site reactions. Development of Factor VIII inhibitors is a potential side effect.

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Octocog alfa (Coagulation Factor VIII) – Uses, Dosage, and Brands in UAE