Octocog alfa (Coagulation Factor VIII) (RECOMBINATE) – Uses, Dosage & Brands in UAE

About Octocog alfa (Coagulation Factor VIII)

Class: | Antihemophilic Agent, Recombinant Coagulation Factor VIII Use: | Octocog alfa is used for the treatment and prophylaxis of bleeding in patients with hemophilia A (congenital factor VIII deficiency). Adult dose: | The dose is individualized based on the severity of factor VIII deficiency, the location and extent of bleeding, and the patient's clinical condition. For minor bleeding episodes, 20-40 IU/kg may be administered. For moderate to major bleeding, 30-50 IU/kg may be required. Pr

Drug Class

Antihemophilic Agent, Recombinant Coagulation Factor VIII

Uses & Indications

Octocog alfa is used for the treatment and prophylaxis of bleeding in patients with hemophilia A (congenital factor VIII deficiency).

Storage Requirements

Store in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. The product can be stored at room temperature (up to 25°C or 77°F) for a limited period, as specified by the manufacturer, but must be used within that time frame. Protect from light.

Manufacturer & Packaging

Manufacturer: Baxter S.A., BELGIUM

Package Size

1 Vial (Powder) + 1 Vial Solvent (10ml)

Price & Supplier

Price in UAE: AED 3680.50

Dosage Information

Adult Dose

The dose is individualized based on the severity of factor VIII deficiency, the location and extent of bleeding, and the patient's clinical condition. For minor bleeding episodes, 20-40 IU/kg may be administered. For moderate to major bleeding, 30-50 IU/kg may be required. Prophylactic dosing typically ranges from 20-40 IU/kg administered 2-3 times per week.

Pediatric Dose

Dosing in pediatric patients is similar to adults and is based on body weight and the severity of the condition. The same dosing principles apply, with adjustments made for the child's weight and clinical response.

Side Effects

Common side effects include headache, fever, chills, flushing, nausea, vomiting, and injection site reactions. Development of inhibitors (antibodies) to factor VIII is a potential complication.

Important Warnings

Monitor for signs of hypersensitivity reactions, including anaphylaxis. Patients should be monitored for the development of factor VIII inhibitors. Use with caution in patients with a history of cardiovascular disease or thromboembolic events. Regularly assess factor VIII levels to ensure adequate dosing.

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Octocog alfa (Coagulation Factor VIII) – Uses, Dosage, and Brands in UAE