About Nitisinone
Class: | Orphan drug, Enzyme inhibitor
Use: | Treatment of hereditary tyrosinemia type 1 (HT-1)
Adult dose: | Initial dose of 2 mg/kg/day, may be increased to a maximum of 10 mg/kg/day based on clinical response and tolerance
Pediatric dose: | Initial dose of 1 mg/kg/day for infants, may be increased to a maximum of 10 mg/kg/day based on clinical response and tolerance
Side effects: | Common side effects include nausea, vomiting, diarrhea, abdominal pain, and decreased appetite
Contrai
Drug Class
Orphan drug, Enzyme inhibitor
Uses & Indications
Treatment of hereditary tyrosinemia type 1 (HT-1)
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from light and moisture
Manufacturer & Packaging
Manufacturer: Swedish Orphan, SWEDEN
Package Size
60's Plastic Bottle
Price & Supplier
Price in UAE: AED 11040.00
Dosage Information
Adult Dose
Initial dose of 2 mg/kg/day, may be increased to a maximum of 10 mg/kg/day based on clinical response and tolerance
Pediatric Dose
Initial dose of 1 mg/kg/day for infants, may be increased to a maximum of 10 mg/kg/day based on clinical response and tolerance
Side Effects
Common side effects include nausea, vomiting, diarrhea, abdominal pain, and decreased appetite
Contraindications & Precautions
Hypersensitivity to nitisinone or any component of the formulation; caution in patients with liver dysfunction
Important Warnings
Risk of developing corneal deposits and ocular toxicity; monitor for signs of liver dysfunction; regular monitoring of plasma tyrosine levels is recommended
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.