About Palonosetron Hydrochloride
            
            Class: | 5-HT3 receptor antagonist  
Use: | Prevention of nausea and vomiting associated with chemotherapy and surgery  
Adult dose: | 0.25 mg IV administered as a single dose 30 minutes before chemotherapy or surgery  
Pediatric dose: | Safety and efficacy not established in children under 1 month; for children 1 month to 17 years, the recommended dose is 20 mcg/kg (up to a maximum of 0.25 mg) IV 30 minutes before chemotherapy  
Side effects: | Headache, constipation, dizziness, fatigue, and in
         
        
            
                
                
                    
                        Drug Class
                    
                    5-HT3 receptor antagonist
                 
                
                
                    
                        Uses & Indications
                    
                    Prevention of nausea and vomiting associated with chemotherapy and surgery
                 
                
                
                    
                        Storage Requirements
                    
                    Store at 20°C to 25°C (68°F to 77°F); protect from light; do not freeze
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Seacross Pharmaceuticals Ltd., United Kingdom
                    
                    
                    Package Size
                    1s
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 283.00
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        0.25 mg IV administered as a single dose 30 minutes before chemotherapy or surgery
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in children under 1 month; for children 1 month to 17 years, the recommended dose is 20 mcg/kg (up to a maximum of 0.25 mg) IV 30 minutes before chemotherapy
                    
                 
                
                
                    
                        Side Effects
                    
                    Headache, constipation, dizziness, fatigue, and injection site reactions
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Known hypersensitivity to palonosetron or any component of the formulation
         
        
        
            
                Important Warnings
            
            Risk of serotonin syndrome when used with other serotonergic drugs; monitor for signs of hypersensitivity reactions; not recommended for use in patients with a history of bowel obstruction or severe constipation
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.