About Phenoxybenzamine Hydrochloride
Class: | Alpha-adrenergic antagonist
Use: | Treatment of pheochromocytoma (a tumor of the adrenal gland that secretes catecholamines) to control hypertension and other symptoms associated with catecholamine excess.
Adult dose: | Initial dose is typically 10 mg orally once daily, which may be increased to 20 mg to 40 mg per day based on clinical response, divided into two or three doses.
Pediatric dose: | Safety and efficacy have not been established in pediatric patients; use is not recomm
Drug Class
Alpha-adrenergic antagonist
Uses & Indications
Treatment of pheochromocytoma (a tumor of the adrenal gland that secretes catecholamines) to control hypertension and other symptoms associated with catecholamine excess.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from light and moisture.
Manufacturer & Packaging
Manufacturer: Forley Ltd., IRELAND
Package Size
30's
Price & Supplier
Price in UAE: AED 148.35
Dosage Information
Adult Dose
Initial dose is typically 10 mg orally once daily, which may be increased to 20 mg to 40 mg per day based on clinical response, divided into two or three doses.
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; use is not recommended unless directed by a specialist.
Side Effects
Common side effects include dizziness, drowsiness, orthostatic hypotension, nasal congestion, and gastrointestinal disturbances (nausea, vomiting).
Contraindications & Precautions
Contraindicated in patients with hypersensitivity to phenoxybenzamine, patients with a history of myocardial infarction, and those with significant cardiovascular disease.
Important Warnings
Caution is advised in patients with a history of seizures, and it may cause significant hypotension. Monitor blood pressure regularly, especially during dose adjustments. Use with caution in patients with renal impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.