About Phentolamine Mesilate (Mesylate)
Class: | Alpha-adrenergic antagonist
Use: | Treatment of hypertensive episodes associated with pheochromocytoma; reversal of local anesthesia; management of extravasation of vasopressors
Adult dose: | 5 to 10 mg IV, may repeat every 5 to 15 minutes as needed; maximum total dose of 30 mg
Pediatric dose: | Not established; use with caution in children, consult a specialist
Side effects: | Hypotension, tachycardia, dizziness, flushing, nasal congestion, gastrointestinal disturbances
Contr
Drug Class
Alpha-adrenergic antagonist
Uses & Indications
Treatment of hypertensive episodes associated with pheochromocytoma; reversal of local anesthesia; management of extravasation of vasopressors
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: ACE Pharmaceuticals BV, Netherlands
Package Size
1ml Ampoule x 5's
Price & Supplier
Price in UAE: AED 3091.20
Dosage Information
Adult Dose
5 to 10 mg IV, may repeat every 5 to 15 minutes as needed; maximum total dose of 30 mg
Pediatric Dose
Not established; use with caution in children, consult a specialist
Side Effects
Hypotension, tachycardia, dizziness, flushing, nasal congestion, gastrointestinal disturbances
Contraindications & Precautions
Hypersensitivity to phentolamine or any component of the formulation; coronary artery disease; history of myocardial infarction; patients with a history of hypersensitivity to other alpha-adrenergic antagonists
Important Warnings
Monitor blood pressure closely during administration; risk of severe hypotension; use caution in patients with renal impairment, cardiovascular disease, or those receiving other antihypertensive medications; may cause syncope or reflex tachycardia
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.