About Pertuzumab,Trastuzumab,Hyaluronidase
Class: | Monoclonal antibody combination (Pertuzumab and Trastuzumab) with Hyaluronidase as a delivery enhancer
Use: | Treatment of HER2-positive breast cancer in combination with chemotherapy for early and metastatic breast cancer
Adult dose: | 600 mg Pertuzumab and 600 mg Trastuzumab administered subcutaneously every 3 weeks; 20,000 Units of Hyaluronidase for delivery
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended
Side effects: | Common sid
Drug Class
Monoclonal antibody combination (Pertuzumab and Trastuzumab) with Hyaluronidase as a delivery enhancer
Uses & Indications
Treatment of HER2-positive breast cancer in combination with chemotherapy for early and metastatic breast cancer
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: F. Hoffmann-La Roche Ltd., SWITZERLAND
Package Size
1 Glass Vial (10 ml)
Price & Supplier
Price in UAE: AED 24772.50
Dosage Information
Adult Dose
600 mg Pertuzumab and 600 mg Trastuzumab administered subcutaneously every 3 weeks; 20,000 Units of Hyaluronidase for delivery
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended
Side Effects
Common side effects include diarrhea, nausea, fatigue, rash, and infusion-related reactions; potential for cardiac dysfunction
Contraindications & Precautions
Known hypersensitivity to Pertuzumab, Trastuzumab, or Hyaluronidase; pregnancy (category D)
Important Warnings
Monitor for signs of cardiac dysfunction; infusion reactions may occur; fetal harm if administered during pregnancy; use caution in patients with a history of heart disease
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.