About Letermovir
Class: | Antiviral agent, specifically a cytomegalovirus (CMV) DNA polymerase inhibitor
Use: | Prophylaxis of cytomegalovirus (CMV) infection and disease in adult recipients of an allogeneic hematopoietic stem cell transplant
Adult dose: | 480 mg orally once daily, starting within 10 days after transplant and continuing for up to 100 days
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children
Side effects: | Nausea, diarrhea, head
Drug Class
Antiviral agent, specifically a cytomegalovirus (CMV) DNA polymerase inhibitor
Uses & Indications
Prophylaxis of cytomegalovirus (CMV) infection and disease in adult recipients of an allogeneic hematopoietic stem cell transplant
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F)
Manufacturer & Packaging
Manufacturer: MERCK SHARP & DOHME B.V. [Haarlem;Netherlands], Netherlands
Package Size
28's (7's blister x 4)
Price & Supplier
Price in UAE: AED 45138.50
Dosage Information
Adult Dose
480 mg orally once daily, starting within 10 days after transplant and continuing for up to 100 days
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children
Side Effects
Nausea, diarrhea, headache, fatigue, elevated liver enzymes (ALT, AST), and peripheral edema
Contraindications & Precautions
Hypersensitivity to letermovir or any component of the formulation; co-administration with strong CYP3A inducers
Important Warnings
Risk of drug interactions with strong CYP3A inhibitors and inducers; monitor liver function tests; use caution in patients with hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.