About Upadacitinib
Class: | Janus kinase (JAK) inhibitor
Use: | Treatment of moderate to severe rheumatoid arthritis in adults, atopic dermatitis in adults and pediatric patients 12 years and older, and ulcerative colitis in adults.
Adult dose: | 15 mg once daily for rheumatoid arthritis and atopic dermatitis; 30 mg once daily for ulcerative colitis (may be reduced to 15 mg based on clinical response).
Pediatric dose: | For atopic dermatitis in patients 12 years and older: 15 mg once daily; safety and effica
Drug Class
Janus kinase (JAK) inhibitor
Uses & Indications
Treatment of moderate to severe rheumatoid arthritis in adults, atopic dermatitis in adults and pediatric patients 12 years and older, and ulcerative colitis in adults.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Abbvie S.r.l, ITALY
Package Size
30's tablets HDPE Bottle
Price & Supplier
Price in UAE: AED 6094.00
Dosage Information
Adult Dose
15 mg once daily for rheumatoid arthritis and atopic dermatitis; 30 mg once daily for ulcerative colitis (may be reduced to 15 mg based on clinical response).
Pediatric Dose
For atopic dermatitis in patients 12 years and older: 15 mg once daily; safety and efficacy not established for patients under 12 years.
Side Effects
Common side effects include nausea, headache, increased liver enzymes, upper respiratory tract infections, and acne.
Contraindications & Precautions
Known hypersensitivity to upadacitinib or any component of the formulation; active serious infections (e.g., tuberculosis, bacterial, viral, or fungal infections).
Important Warnings
Risk of serious infections, thrombosis, and malignancies; monitor for signs of infection; not recommended for use in patients with severe hepatic impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.