About Rituximab (MABTHERA)
Class: | Monoclonal antibody (anti-CD20)
Use: | Treatment of non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis (RA), and granulomatosis with polyangiitis (GPA)
Adult dose: | 375 mg/m² IV infusion once weekly for 4 weeks for NHL; 500 mg IV infusion on day 1 and 15 for CLL; 1000 mg IV infusion on day 1, 15, and 28 for RA; dosing may vary based on specific indication and treatment protocol
Pediatric dose: | Not established; use in pediatric populations shoul
Drug Class
Monoclonal antibody (anti-CD20)
Uses & Indications
Treatment of non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis (RA), and granulomatosis with polyangiitis (GPA)
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: F. Hoffmann-La Roche Ltd., SWITZERLAND
Package Size
20ml Vial
Price & Supplier
Price in UAE: AED 11711.00
Dosage Information
Adult Dose
375 mg/m² IV infusion once weekly for 4 weeks for NHL; 500 mg IV infusion on day 1 and 15 for CLL; 1000 mg IV infusion on day 1, 15, and 28 for RA; dosing may vary based on specific indication and treatment protocol
Pediatric Dose
Not established; use in pediatric populations should be based on clinical judgment and specific protocols
Side Effects
Infusion reactions, infections, neutropenia, thrombocytopenia, fatigue, fever, chills, nausea, and rash
Contraindications & Precautions
Hypersensitivity to rituximab or any component of the formulation; active severe infections; history of progressive multifocal leukoencephalopathy (PML)
Important Warnings
Risk of severe infusion reactions, infections (including PML), and tumor lysis syndrome; monitor for signs of infection and infusion-related reactions; premedication with antihistamines and/or corticosteroids may be required to reduce infusion reactions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.