About Rituximab
Class: | Monoclonal Antibody (CD20 inhibitor)
Use: | Treatment of adult patients with CD20-positive B-cell non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), and rheumatoid arthritis (RA). Also used in pediatric patients with certain types of NHL.
Adult dose: | 1400 mg administered subcutaneously once every 2 weeks for the first 2 doses, then every 4 weeks thereafter, depending on the indication.
Pediatric dose: | For pediatric patients with NHL, the dosing is typically based
Drug Class
Monoclonal Antibody (CD20 inhibitor)
Uses & Indications
Treatment of adult patients with CD20-positive B-cell non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), and rheumatoid arthritis (RA). Also used in pediatric patients with certain types of NHL.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: F. Hoffmann-La Roche Ltd., SWITZERLAND
Package Size
Vial
Price & Supplier
Price in UAE: AED 9417.50
Dosage Information
Adult Dose
1400 mg administered subcutaneously once every 2 weeks for the first 2 doses, then every 4 weeks thereafter, depending on the indication.
Pediatric Dose
For pediatric patients with NHL, the dosing is typically based on body surface area (BSA), commonly 375 mg/m² administered intravenously for the first dose, followed by subcutaneous dosing as per the specific treatment protocol.
Side Effects
Common side effects include infusion-related reactions, infections, nausea, fatigue, headache, and skin reactions at the injection site.
Contraindications & Precautions
Known hypersensitivity to rituximab or any component of the formulation; active severe infections; and history of progressive multifocal leukoencephalopathy (PML).
Important Warnings
Risk of serious infusion-related reactions, severe mucocutaneous reactions, and infections, including reactivation of hepatitis B virus. Monitor for signs of PML and consider premedication to reduce infusion reactions.
Related Medicines in Same Category
See also: Other Monoclonal Antibody (CD20 inhibitor) medicines available in UAE pharmacies
Ofatumumab
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.