About Tocilizumab
Class: | Monoclonal antibody (IL-6 receptor antagonist)
Use: | Treatment of moderate to severe rheumatoid arthritis, systemic juvenile idiopathic arthritis, giant cell arteritis, and cytokine release syndrome; also used in COVID-19 pneumonia in hospitalized patients requiring supplemental oxygen or mechanical ventilation.
Adult dose: | 4 mg/kg IV infusion, may be increased to 8 mg/kg based on clinical response; dosing may be repeated every 4 weeks.
Pediatric dose: | For systemic juvenile i
Drug Class
Monoclonal antibody (IL-6 receptor antagonist)
Uses & Indications
Treatment of moderate to severe rheumatoid arthritis, systemic juvenile idiopathic arthritis, giant cell arteritis, and cytokine release syndrome; also used in COVID-19 pneumonia in hospitalized patients requiring supplemental oxygen or mechanical ventilation.
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: Roche Registration GmbH, Germany
Package Size
10ml Vial x 4
Price & Supplier
Price in UAE: AED 18354.00
Dosage Information
Adult Dose
4 mg/kg IV infusion, may be increased to 8 mg/kg based on clinical response; dosing may be repeated every 4 weeks.
Pediatric Dose
For systemic juvenile idiopathic arthritis, 12 years and older: 8 mg/kg IV infusion every 2 weeks; for younger children, dosing is based on weight and should be determined by a healthcare provider.
Side Effects
Common side effects include infections, headache, elevated liver enzymes, gastrointestinal perforation, and hypertension.
Contraindications & Precautions
Active infections (e.g., tuberculosis), hypersensitivity to tocilizumab or any component of the formulation, and severe hepatic impairment.
Important Warnings
Risk of serious infections, including tuberculosis; monitor for signs of infection; may cause liver enzyme elevations; avoid use in patients with active infections; caution in patients with a history of diverticulitis due to the risk of gastrointestinal perforation.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.