About Pasireotide
            
            Class: | Somatostatin analog  
Use: | Treatment of Cushing's disease in adults who are not candidates for surgery or for whom surgery has failed  
Adult dose: | Initial dose of 0.6 mg subcutaneously twice daily; may be increased to a maximum of 0.9 mg twice daily based on clinical response and tolerability  
Pediatric dose: | Safety and efficacy not established in pediatric patients  
Side effects: | Diarrhea, nausea, abdominal pain, hyperglycemia, fatigue, injection site reactions  
Contraindic
         
        
            
                
                
                    
                        Drug Class
                    
                    Somatostatin analog
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of Cushing's disease in adults who are not candidates for surgery or for whom surgery has failed
                 
                
                
                    
                        Storage Requirements
                    
                    Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once reconstituted, use immediately or store at 2°C to 8°C (36°F to 46°F) for up to 24 hours
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Recordati Rare Diseases, France
                    
                    
                    Package Size
                    1 Kit [1 Glass Vial of Powder + 1 Pre-filled syringe with 2 ml Solvent + 1 Safety injection Needle + 1 Vial Adapter ]
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 15509.00
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        Initial dose of 0.6 mg subcutaneously twice daily; may be increased to a maximum of 0.9 mg twice daily based on clinical response and tolerability
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients
                    
                 
                
                
                    
                        Side Effects
                    
                    Diarrhea, nausea, abdominal pain, hyperglycemia, fatigue, injection site reactions
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Known hypersensitivity to pasireotide or any component of the formulation; severe hepatic impairment
         
        
        
            
                Important Warnings
            
            Risk of hyperglycemia; monitor blood glucose levels; may cause gallbladder disease; caution in patients with diabetes or glucose intolerance; potential for QT prolongation; monitor cardiac function in at-risk patients
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.