About Sodium Thiosulfate
Class: | Antidote; Chelating Agent
Use: | Sodium thiosulfate is primarily used as an antidote for cyanide poisoning. It is also used off-label for the treatment of calciphylaxis in patients with chronic kidney disease.
Adult dose: | For cyanide poisoning, the typical dose is 12.5 grams (50 ml of 25% solution) administered intravenously over 10 to 30 minutes.
Pediatric dose: | For cyanide poisoning, the dose is 400 mg/kg (1.65 ml/kg of 25% solution) intravenously, not to exceed 12.5 grams.
Drug Class
Antidote; Chelating Agent
Uses & Indications
Sodium thiosulfate is primarily used as an antidote for cyanide poisoning. It is also used off-label for the treatment of calciphylaxis in patients with chronic kidney disease.
Storage Requirements
Store at controlled room temperature, 20°C to 25°C (68°F to 77°F). Protect from light and freezing.
Manufacturer & Packaging
Manufacturer: American Regent Laboratories, U.S.A
Package Size
50ml Vial
Price & Supplier
Price in UAE: AED 112.00
Dosage Information
Adult Dose
For cyanide poisoning, the typical dose is 12.5 grams (50 ml of 25% solution) administered intravenously over 10 to 30 minutes.
Pediatric Dose
For cyanide poisoning, the dose is 400 mg/kg (1.65 ml/kg of 25% solution) intravenously, not to exceed 12.5 grams.
Side Effects
Common side effects include nausea, vomiting, joint pain, headache, and disorientation. Hypotension and allergic reactions may also occur.
Contraindications & Precautions
Contraindicated in patients with known hypersensitivity to sodium thiosulfate. Caution is advised in patients with severe renal impairment.
Important Warnings
Rapid intravenous administration may cause hypotension. Monitor blood pressure and renal function during treatment. Use with caution in patients with pre-existing cardiovascular conditions.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.