About Topotecan Hydrochloride
Class: | Antineoplastic agent, Topoisomerase I inhibitor
Use: | Treatment of metastatic ovarian cancer, small cell lung cancer, and as a second-line therapy for certain types of cancer
Adult dose: | 1.5 mg/m² IV infusion over 30 minutes once daily for 5 consecutive days, repeated every 21 days
Pediatric dose: | Not established; use in pediatric patients should be based on clinical judgment and careful consideration of risks and benefits
Side effects: | Nausea, vomiting, diarrhea, fatigue
Drug Class
Antineoplastic agent, Topoisomerase I inhibitor
Uses & Indications
Treatment of metastatic ovarian cancer, small cell lung cancer, and as a second-line therapy for certain types of cancer
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Hospira Limited, UNITED KINGDOM
Package Size
4ml Glass Vial x 5
Price & Supplier
Price in UAE: AED 3068.00
Dosage Information
Adult Dose
1.5 mg/m² IV infusion over 30 minutes once daily for 5 consecutive days, repeated every 21 days
Pediatric Dose
Not established; use in pediatric patients should be based on clinical judgment and careful consideration of risks and benefits
Side Effects
Nausea, vomiting, diarrhea, fatigue, anemia, neutropenia, thrombocytopenia, alopecia
Contraindications & Precautions
Hypersensitivity to topotecan or any component of the formulation; patients with severely impaired bone marrow function
Important Warnings
Risk of myelosuppression; monitor blood counts regularly; may cause fetal harm; use caution in patients with renal impairment; avoid use in pregnancy unless necessary
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.