About Trametinib-Dimethylsulfoxide
Class: | Antineoplastic agent, MEK inhibitor
Use: | Treatment of unresectable or metastatic melanoma with BRAF V600E or V600K mutations; used in combination with dabrafenib for BRAF V600E or V600K mutation-positive non-small cell lung cancer (NSCLC)
Adult dose: | 2 mg orally once daily, taken at the same time each day, with or without food
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Common side effects include rash, diarrhea, edema, fatigue
Drug Class
Antineoplastic agent, MEK inhibitor
Uses & Indications
Treatment of unresectable or metastatic melanoma with BRAF V600E or V600K mutations; used in combination with dabrafenib for BRAF V600E or V600K mutation-positive non-small cell lung cancer (NSCLC)
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: NOVARTIS EUROPHARM LIMITED, IRELAND
Package Size
30's
Price & Supplier
Price in UAE: AED 20704.50
Dosage Information
Adult Dose
2 mg orally once daily, taken at the same time each day, with or without food
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Common side effects include rash, diarrhea, edema, fatigue, nausea, and elevated liver enzymes
Contraindications & Precautions
Hypersensitivity to trametinib or any component of the formulation; pregnancy and breastfeeding
Important Warnings
Risk of serious skin reactions, including rash and dermatitis; risk of cardiomyopathy; monitor for signs of bleeding; avoid use in patients with severe hepatic impairment; not recommended during pregnancy due to potential fetal harm
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.