About Ataluren
Class: | Nonsense mutation read-through agent
Use: | Treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the dystrophin gene that is amenable to nonsense mutation read-through
Adult dose: | 10 mg/kg orally three times a day, with a maximum dose of 40 mg/kg/day
Pediatric dose: | 10 mg/kg orally three times a day, with a maximum dose of 40 mg/kg/day; dosing may vary based on weight and clinical response
Side effects: | Common side effects include diarrhe
Drug Class
Nonsense mutation read-through agent
Uses & Indications
Treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the dystrophin gene that is amenable to nonsense mutation read-through
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: PTC Therapeutics International Limited., IRELAND
Package Size
125mg Sachet x 30
Price & Supplier
Price in UAE: AED 19336.22
Dosage Information
Adult Dose
10 mg/kg orally three times a day, with a maximum dose of 40 mg/kg/day
Pediatric Dose
10 mg/kg orally three times a day, with a maximum dose of 40 mg/kg/day; dosing may vary based on weight and clinical response
Side Effects
Common side effects include diarrhea, nausea, vomiting, headache, and decreased appetite
Contraindications & Precautions
Hypersensitivity to ataluren or any component of the formulation; caution in patients with renal impairment
Important Warnings
Risk of renal impairment; monitor renal function; not recommended for use in patients with significant renal impairment; potential for drug interactions with other medications affecting renal function or metabolism
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.