About Laropiprant,Nicotinic Acid (Niacin)
Class: | Combination of a prostaglandin receptor antagonist (Laropiprant) and a lipid-altering agent (Nicotinic Acid)
Use: | Used for the treatment of dyslipidemia, specifically to lower LDL cholesterol and triglycerides while raising HDL cholesterol in patients at risk for cardiovascular disease
Adult dose: | 20 mg of Laropiprant and 1 g of Nicotinic Acid (Niacin) once daily, taken with food to minimize flushing
Pediatric dose: | Safety and efficacy not established in pediatric patients;
Drug Class
Combination of a prostaglandin receptor antagonist (Laropiprant) and a lipid-altering agent (Nicotinic Acid)
Uses & Indications
Used for the treatment of dyslipidemia, specifically to lower LDL cholesterol and triglycerides while raising HDL cholesterol in patients at risk for cardiovascular disease
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from moisture and light
Manufacturer & Packaging
Manufacturer: Merck Sharp & Dohme Limited, UNITED KINGDOM
Package Size
56's (7's Blister x 8)
Price & Supplier
Price in UAE: AED 198.50
Dosage Information
Adult Dose
20 mg of Laropiprant and 1 g of Nicotinic Acid (Niacin) once daily, taken with food to minimize flushing
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children
Side Effects
Flushing, pruritus, gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, dizziness, and potential liver enzyme elevation
Contraindications & Precautions
Hypersensitivity to any component of the formulation, active liver disease, severe gout, and persistent elevated transaminases
Important Warnings
Risk of hepatotoxicity, especially with high doses of Niacin; monitor liver function tests; may cause serious skin reactions; caution in patients with diabetes, as it may affect glucose control; avoid use with other medications that can cause liver damage
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.