About Vasopressin
Class: | Antidiuretic hormone (ADH) analog; Vasopressor
Use: | Treatment of diabetes insipidus due to deficiency of endogenous vasopressin; management of vasodilatory shock (e.g., septic shock) to increase blood pressure; off-label use includes treatment of esophageal variceal bleeding.
Adult dose: | Diabetes insipidus: 5 to 10 units subcutaneously or intramuscularly 2 to 4 times daily as needed. Shock: Initial dose of 0.01 to 0.03 units/minute IV infusion, titrated to effect.
Pediatric do
Drug Class
Antidiuretic hormone (ADH) analog; Vasopressor
Uses & Indications
Treatment of diabetes insipidus due to deficiency of endogenous vasopressin; management of vasodilatory shock (e.g., septic shock) to increase blood pressure; off-label use includes treatment of esophageal variceal bleeding.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F). Protect from light. Do not freeze.
Manufacturer & Packaging
Manufacturer: American Regent Laboratories, U.S.A
Package Size
1 Vial x 25
Price & Supplier
Price in UAE: AED 1500.00
Dosage Information
Adult Dose
Diabetes insipidus: 5 to 10 units subcutaneously or intramuscularly 2 to 4 times daily as needed. Shock: Initial dose of 0.01 to 0.03 units/minute IV infusion, titrated to effect.
Pediatric Dose
Diabetes insipidus: 0.0005 units/kg subcutaneously or intramuscularly every 8 to 12 hours, adjusted based on response and tolerance.
Side Effects
Common side effects include headache, nausea, abdominal cramps, tremor, sweating, and paleness. Serious side effects may include hyponatremia, water intoxication, and vasoconstriction leading to ischemia.
Contraindications & Precautions
Contraindicated in patients with hypersensitivity to vasopressin or any component of the formulation, and in patients with chronic nephritis with nitrogen retention. Use with caution in patients with vascular disease, asthma, epilepsy, migraine, heart failure, or renal impairment.
Important Warnings
Use with caution in patients with cardiovascular disease due to the risk of cardiac ischemia. Monitor fluid and electrolyte balance to prevent water intoxication and hyponatremia. Adjust dose in patients with renal impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.