About Panitumumab
Class: | Monoclonal antibody (EGFR inhibitor)
Use: | Treatment of metastatic colorectal cancer (mCRC) in patients with wild-type KRAS genes, as a single agent or in combination with chemotherapy.
Adult dose: | 6 mg/kg administered intravenously every 14 days.
Pediatric dose: | Safety and efficacy in pediatric patients have not been established; not recommended for use in this population.
Side effects: | Common side effects include skin rash, diarrhea, fatigue, nausea, and infusion-relate
Drug Class
Monoclonal antibody (EGFR inhibitor)
Uses & Indications
Treatment of metastatic colorectal cancer (mCRC) in patients with wild-type KRAS genes, as a single agent or in combination with chemotherapy.
Storage Requirements
Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: Amgen Europe B.V., NETHERLANDS
Package Size
20ml Vial
Price & Supplier
Price in UAE: AED 13872.50
Dosage Information
Adult Dose
6 mg/kg administered intravenously every 14 days.
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; not recommended for use in this population.
Side Effects
Common side effects include skin rash, diarrhea, fatigue, nausea, and infusion-related reactions.
Contraindications & Precautions
Known hypersensitivity to panitumumab or any component of the formulation; patients with wild-type KRAS mutations should not receive this therapy.
Important Warnings
Risk of severe skin reactions, infusion-related reactions, and electrolyte imbalances (e.g., hypomagnesemia). Monitor for dermatologic toxicities and electrolyte levels during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.