About Azacitidine
            
            Class: | Antineoplastic agent, Hypomethylating agent  
Use: | Treatment of myelodysplastic syndromes (MDS), acute myeloid leukemia (AML) in patients who are not candidates for more intensive therapy  
Adult dose: | 75 mg/m² subcutaneously once daily for 7 days in a 28-day cycle; may be increased to 100 mg/m² based on tolerance and response  
Pediatric dose: | Safety and efficacy have not been established in pediatric patients  
Side effects: | Nausea, vomiting, diarrhea, fatigue, injection site 
         
        
            
                
                
                    
                        Drug Class
                    
                    Antineoplastic agent, Hypomethylating agent
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of myelodysplastic syndromes (MDS), acute myeloid leukemia (AML) in patients who are not candidates for more intensive therapy
                 
                
                
                    
                        Storage Requirements
                    
                    Store in the refrigerator (2°C to 8°C); do not freeze; protect from light; discard unused portion after 28 days
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Pharmion, U.S.A
                    
                    
                    Package Size
                    10 Vials
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 26162.50
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        75 mg/m² subcutaneously once daily for 7 days in a 28-day cycle; may be increased to 100 mg/m² based on tolerance and response
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy have not been established in pediatric patients
                    
                 
                
                
                    
                        Side Effects
                    
                    Nausea, vomiting, diarrhea, fatigue, injection site reactions, thrombocytopenia, anemia, leukopenia
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to azacitidine or any component of the formulation; advanced malignant hepatic tumors
         
        
        
            
                Important Warnings
            
            Risk of myelosuppression; monitor blood counts regularly; potential for tumor lysis syndrome; may cause fetal harm; use caution in patients with renal or hepatic impairment
         
        
        
        
        
        
        
        
            
                Related Medicines in Same Category
            
            
                See also: Other Antineoplastic agent, Hypomethylating agent medicines available in UAE pharmacies
            
            
            
                Decitabine
            
            
         
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.