About NIRAPARIB
            
            Class: | PARP inhibitor  
Use: | Treatment of adult patients with recurrent ovarian cancer, including those with BRCA mutation, following response to platinum-based chemotherapy  
Adult dose: | 300 mg orally once daily  
Pediatric dose: | Safety and efficacy not established in pediatric patients  
Side effects: | Nausea, fatigue, anemia, thrombocytopenia, vomiting, constipation, abdominal pain, headache  
Contraindications: | Hypersensitivity to niraparib or any component of the formulation; sev
         
        
            
                
                
                    
                        Drug Class
                    
                    PARP inhibitor
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of adult patients with recurrent ovarian cancer, including those with BRCA mutation, following response to platinum-based chemotherapy
                 
                
                
                    
                        Storage Requirements
                    
                    Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: GlaxoSmithKline Ireland Limited, Ireland
                    
                    
                    Package Size
                    84'S
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 31663.80
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        300 mg orally once daily
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients
                    
                 
                
                
                    
                        Side Effects
                    
                    Nausea, fatigue, anemia, thrombocytopenia, vomiting, constipation, abdominal pain, headache
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to niraparib or any component of the formulation; severe thrombocytopenia or anemia prior to treatment
         
        
        
            
                Important Warnings
            
            Risk of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML); monitor complete blood counts regularly; risk of hypertension; may cause embryo-fetal toxicity; not recommended during pregnancy or breastfeeding
         
        
        
        
        
        
        
        
            
                Related Medicines in Same Category
            
            
                See also: Other PARP inhibitor medicines available in UAE pharmacies
            
            
            
                Olaparib
            
            
            
                Olaparib
            
            
            
                Olaparib
            
            
         
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.