About Vorinostat
            
            Class: | Histone deacetylase inhibitor  
Use: | Treatment of cutaneous manifestations of advanced primary cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy  
Adult dose: | 400 mg orally once daily, taken with food; may be adjusted based on tolerance and response  
Pediatric dose: | Safety and efficacy not established in pediatric patients  
Side effects: | Diarrhea, fatigue, nausea, vomiting, anorexia, weight loss, thrombocytopenia, and anemia  
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                        Drug Class
                    
                    Histone deacetylase inhibitor
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of cutaneous manifestations of advanced primary cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Merck Sharp & Dohme Pty Limited, AUSTRALIA
                    
                    
                    Package Size
                    120s
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 23460.00
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        400 mg orally once daily, taken with food; may be adjusted based on tolerance and response
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients
                    
                 
                
                
                    
                        Side Effects
                    
                    Diarrhea, fatigue, nausea, vomiting, anorexia, weight loss, thrombocytopenia, and anemia
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to vorinostat or any component of the formulation; pregnancy (Category D)
         
        
        
            
                Important Warnings
            
            Risk of thrombocytopenia, gastrointestinal bleeding, and potential for serious skin reactions; monitor blood counts regularly; may cause fetal harm if administered during pregnancy
         
        
        
        
        
        
        
        
            
                Related Medicines in Same Category
            
            
                See also: Other Histone deacetylase inhibitor medicines available in UAE pharmacies
            
            
            
                Romidepsin
            
            
         
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.