About Acalabrutinib
Class: | Bruton's tyrosine kinase (BTK) inhibitor
Use: | Treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), and for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy
Adult dose: | 100 mg orally twice daily
Pediatric dose: | Safety and efficacy in pediatric patients have not been established
Side effects: | Common side effects include headache, diarrhea, fatigue, nausea, and in
Drug Class
Bruton's tyrosine kinase (BTK) inhibitor
Uses & Indications
Treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), and for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F)
Manufacturer & Packaging
Manufacturer: AstraZeneca UK Limited, UNITED KINGDOM
Package Size
60's (6 x 10's)
Price & Supplier
Price in UAE: AED 57416.00
Dosage Information
Adult Dose
100 mg orally twice daily
Pediatric Dose
Safety and efficacy in pediatric patients have not been established
Side Effects
Common side effects include headache, diarrhea, fatigue, nausea, and increased risk of infections
Contraindications & Precautions
Hypersensitivity to acalbrutinib or any component of the formulation; severe hepatic impairment (Child-Pugh Class C)
Important Warnings
Risk of bleeding, including serious bleeding events; monitor for signs of infection; may cause atrial fibrillation; caution in patients with a history of cardiac arrhythmias or those on anticoagulants
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.