About Zanubrutinib
Class: | Bruton's tyrosine kinase (BTK) inhibitor
Use: | Treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy; treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)
Adult dose: | 160 mg orally twice daily or 320 mg orally once daily for MCL; 80 mg orally once daily for CLL/SLL
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Diarrhea, fatigue, m
Drug Class
Bruton's tyrosine kinase (BTK) inhibitor
Uses & Indications
Treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy; treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: BEIGENE USA, INC., United States of America
Package Size
120's HDPE bottle
Price & Supplier
Price in UAE: AED 64086.00
Dosage Information
Adult Dose
160 mg orally twice daily or 320 mg orally once daily for MCL; 80 mg orally once daily for CLL/SLL
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Diarrhea, fatigue, musculoskeletal pain, rash, upper respiratory tract infections, and increased liver enzymes
Contraindications & Precautions
Hypersensitivity to zanubrutinib or any component of the formulation; concurrent use with strong CYP3A inhibitors
Important Warnings
Risk of bleeding; monitor for signs of infection; may cause atrial fibrillation; liver function should be monitored; avoid use in patients with severe hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.