About Ibrutinib
Class: | Bruton's tyrosine kinase (BTK) inhibitor
Use: | Treatment of chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and mantle cell lymphoma (MCL); also indicated for Waldenström's macroglobulinemia and chronic graft-versus-host disease (cGVHD)
Adult dose: | 140 mg orally once daily
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Diarrhea, fatigue, nausea, neutropenia, thrombocytopenia, anemia, rash, and increased risk o
Drug Class
Bruton's tyrosine kinase (BTK) inhibitor
Uses & Indications
Treatment of chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and mantle cell lymphoma (MCL); also indicated for Waldenström's macroglobulinemia and chronic graft-versus-host disease (cGVHD)
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Janseen Cilag International, Belgium
Package Size
30's (10's Blister 3)
Price & Supplier
Price in UAE: AED 9026.50
Dosage Information
Adult Dose
140 mg orally once daily
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Diarrhea, fatigue, nausea, neutropenia, thrombocytopenia, anemia, rash, and increased risk of infections
Contraindications & Precautions
Hypersensitivity to ibrutinib or any component of the formulation; concurrent use with strong CYP3A inhibitors
Important Warnings
Risk of bleeding, including serious and fatal hemorrhage; monitor for signs of infection; may cause atrial fibrillation; monitor blood counts regularly; avoid use in patients with severe hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.