About Clozapine
Class: | Atypical antipsychotic
Use: | Treatment-resistant schizophrenia and reduction of suicidal behavior in patients with schizophrenia or schizoaffective disorder
Adult dose: | Initial: 12.5 mg once daily; Maintenance: 300-450 mg daily, may increase to 600 mg based on clinical response and tolerability
Pediatric dose: | Not established; use in children under 16 years is not recommended
Side effects: | Sedation, hypersalivation, weight gain, seizures, agranulocytosis, myocarditis, car
Drug Class
Atypical antipsychotic
Uses & Indications
Treatment-resistant schizophrenia and reduction of suicidal behavior in patients with schizophrenia or schizoaffective disorder
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Novartis, TURKEY
Package Size
50s
Price & Supplier
Price in UAE: AED 139.50
Dosage Information
Adult Dose
Initial: 12.5 mg once daily; Maintenance: 300-450 mg daily, may increase to 600 mg based on clinical response and tolerability
Pediatric Dose
Not established; use in children under 16 years is not recommended
Side Effects
Sedation, hypersalivation, weight gain, seizures, agranulocytosis, myocarditis, cardiomyopathy
Contraindications & Precautions
History of agranulocytosis, severe bone marrow suppression, uncontrolled epilepsy, hypersensitivity to clozapine
Important Warnings
Risk of agranulocytosis; monitor white blood cell counts; increased risk of seizures; may cause metabolic syndrome; use with caution in patients with cardiovascular disease or history of seizures
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.