About Clozapine
Class: | Antipsychotic (Atypical)
Use: | Treatment-resistant schizophrenia and reduction of suicidal behavior in patients with schizophrenia or schizoaffective disorder
Adult dose: | Initial dose of 12.5 mg once daily, may be increased to 25 mg after 1-2 days; typical maintenance dose ranges from 300 mg to 450 mg daily, with a maximum dose of 900 mg per day
Pediatric dose: | Not approved for use in pediatric patients under 16 years; use in adolescents (16-17 years) should be carefully cons
Drug Class
Antipsychotic (Atypical)
Uses & Indications
Treatment-resistant schizophrenia and reduction of suicidal behavior in patients with schizophrenia or schizoaffective disorder
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Novartis Pharma AG, SWITZERLAND
Package Size
50's (10's Blister x 5)
Price & Supplier
Price in UAE: AED 172.50
Dosage Information
Adult Dose
Initial dose of 12.5 mg once daily, may be increased to 25 mg after 1-2 days; typical maintenance dose ranges from 300 mg to 450 mg daily, with a maximum dose of 900 mg per day
Pediatric Dose
Not approved for use in pediatric patients under 16 years; use in adolescents (16-17 years) should be carefully considered and monitored
Side Effects
Common side effects include sedation, hypersalivation, weight gain, constipation, seizures, and agranulocytosis
Contraindications & Precautions
History of agranulocytosis or severe granulocytopenia, uncontrolled epilepsy, severe liver disease, and hypersensitivity to clozapine or any component of the formulation
Important Warnings
Risk of agranulocytosis; regular monitoring of white blood cell counts is essential; may cause seizures, myocarditis, cardiomyopathy, and metabolic syndrome; use with caution in patients with a history of seizures or cardiovascular disease
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.