About Crizotinib
Class: | Tyrosine kinase inhibitor
Use: | Treatment of anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) and ROS1-positive NSCLC
Adult dose: | 250 mg orally twice daily
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Nausea, diarrhea, vomiting, constipation, fatigue, visual disturbances, liver enzyme elevations, peripheral edema
Contraindications: | Hypersensitivity to crizotinib or any component of the f
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) and ROS1-positive NSCLC
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light and moisture
Manufacturer & Packaging
Manufacturer: Pfizer Pharmaceuticals L.L.C., U.S.A
Package Size
60's HDPE Bottle
Price & Supplier
Price in UAE: AED 31643.00
Dosage Information
Adult Dose
250 mg orally twice daily
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Nausea, diarrhea, vomiting, constipation, fatigue, visual disturbances, liver enzyme elevations, peripheral edema
Contraindications & Precautions
Hypersensitivity to crizotinib or any component of the formulation; severe liver impairment
Important Warnings
Risk of hepatotoxicity, interstitial lung disease, QT prolongation, and severe bradycardia; monitor liver function tests and ECG regularly
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.