About Glibenclamide,Metformin Hydrochloride
Class: | Antidiabetic agent (sulfonylurea and biguanide combination)
Use: | Management of type 2 diabetes mellitus in adults when diet and exercise alone do not provide adequate glycemic control
Adult dose: | Glibenclamide 2.5 mg and Metformin 500 mg taken orally, typically starting with one tablet twice daily, with adjustments based on blood glucose levels
Pediatric dose: | Not established; use in pediatric patients is not recommended
Side effects: | Common side effects include gastroin
Drug Class
Antidiabetic agent (sulfonylurea and biguanide combination)
Uses & Indications
Management of type 2 diabetes mellitus in adults when diet and exercise alone do not provide adequate glycemic control
Storage Requirements
Store at room temperature (15°C to 30°C or 59°F to 86°F) in a tightly closed container, protected from moisture and light
Manufacturer & Packaging
Manufacturer: Globalpharma CO. L.L.C., U.A.E
Package Size
30's (10's Blister x 3)
Price & Supplier
Price in UAE: AED 14.50
Dosage Information
Adult Dose
Glibenclamide 2.5 mg and Metformin 500 mg taken orally, typically starting with one tablet twice daily, with adjustments based on blood glucose levels
Pediatric Dose
Not established; use in pediatric patients is not recommended
Side Effects
Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), hypoglycemia, headache, dizziness, and abdominal discomfort
Contraindications & Precautions
Contraindicated in patients with hypersensitivity to glibenclamide, metformin, or any component of the formulation; severe renal impairment; acute or chronic metabolic acidosis; diabetic ketoacidosis; and conditions associated with hypoxia
Important Warnings
Risk of lactic acidosis, particularly in patients with renal impairment, liver disease, or those undergoing procedures involving contrast media; monitor renal function regularly; caution in patients with a history of cardiovascular disease or dehydration
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.