About Encorafenib
Class: | BRAF inhibitor
Use: | Treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with binimetinib; also used for other BRAF V600 mutation-positive cancers.
Adult dose: | 75 mg orally once daily, taken continuously until disease progression or unacceptable toxicity.
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children.
Side effects: | Common side effects inclu
Drug Class
BRAF inhibitor
Uses & Indications
Treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with binimetinib; also used for other BRAF V600 mutation-positive cancers.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Array BioPharma Inc., United States of America
Package Size
180's (2 X 90's) Bottle
Price & Supplier
Price in UAE: AED 24643.71
Dosage Information
Adult Dose
75 mg orally once daily, taken continuously until disease progression or unacceptable toxicity.
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children.
Side Effects
Common side effects include fatigue, nausea, diarrhea, decreased appetite, rash, and headache.
Contraindications & Precautions
Hypersensitivity to encorafenib or any component of the formulation; use with caution in patients with a history of skin cancers.
Important Warnings
Risk of new malignancies (cutaneous squamous cell carcinoma, melanoma); serious skin reactions; hepatotoxicity; QT prolongation; use with caution in patients with a history of cardiac issues.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.