About Cyclophosphamide
Class: | Alkylating agent, Antineoplastic agent
Use: | Cyclophosphamide is used in the treatment of various types of cancer, including lymphomas, leukemias, breast cancer, ovarian cancer, and multiple myeloma. It is also used in certain autoimmune disorders, such as nephrotic syndrome and severe rheumatoid arthritis.
Adult dose: | The typical oral dose for adults varies widely depending on the condition being treated, ranging from 1 to 5 mg/kg/day. Dosage must be individualized based on the
Drug Class
Alkylating agent, Antineoplastic agent
Uses & Indications
Cyclophosphamide is used in the treatment of various types of cancer, including lymphomas, leukemias, breast cancer, ovarian cancer, and multiple myeloma. It is also used in certain autoimmune disorders, such as nephrotic syndrome and severe rheumatoid arthritis.
Storage Requirements
Store at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from light and moisture.
Manufacturer & Packaging
Manufacturer: Baxter, GERMANY
Package Size
Blister Pack x 50 tablets
Price & Supplier
Price in UAE: AED 131.10
Dosage Information
Adult Dose
The typical oral dose for adults varies widely depending on the condition being treated, ranging from 1 to 5 mg/kg/day. Dosage must be individualized based on the specific condition, patient response, and other factors.
Pediatric Dose
Pediatric dosing also varies based on the condition and is typically calculated by body surface area (BSA) or weight, often ranging from 2 to 5 mg/kg/day. Specific dosing should be determined by a healthcare professional.
Side Effects
Common side effects include nausea, vomiting, alopecia (hair loss), leukopenia (low white blood cell count), anemia, thrombocytopenia (low platelet count), and potential for hemorrhagic cystitis.
Contraindications & Precautions
Contraindicated in patients with hypersensitivity to cyclophosphamide or any component of the formulation, and in those with severely depressed bone marrow function. It should not be used in patients with active infections or urinary outflow obstruction.
Important Warnings
Cyclophosphamide can cause severe bone marrow suppression, leading to increased risk of infection and bleeding. It has potential carcinogenic, mutagenic, and teratogenic effects. Adequate hydration and frequent urination are recommended to prevent hemorrhagic cystitis. Regular monitoring of blood counts and renal function is essential. Use with caution in patients with renal or hepatic impairment.
Related Medicines in Same Category
See also: Other Alkylating agent, Antineoplastic agent medicines available in UAE pharmacies
Ifosfamide
Ifosfamide
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.