About Epoprostenol
Class: | Prostacyclin analog
Use: | Treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and symptoms; also used in severe cases of primary pulmonary hypertension.
Adult dose: | Initial dose of 2 ng/kg/min via continuous intravenous infusion, titrated to effect, typically up to 20 ng/kg/min.
Pediatric dose: | Not established; use in pediatric patients should be based on clinical judgment and careful monitoring.
Side effects: | Flushing, headache, gastrointestin
Drug Class
Prostacyclin analog
Uses & Indications
Treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and symptoms; also used in severe cases of primary pulmonary hypertension.
Storage Requirements
Store lyophilized powder at room temperature (20-25°C or 68-77°F); reconstituted solution should be used immediately or stored at 2-8°C (36-46°F) for up to 24 hours.
Manufacturer & Packaging
Manufacturer: SUN PHARMACEUTICALS INDUSTRIES Inc, United States of America
Package Size
Vial
Price & Supplier
Price in UAE: AED 300.00
Dosage Information
Adult Dose
Initial dose of 2 ng/kg/min via continuous intravenous infusion, titrated to effect, typically up to 20 ng/kg/min.
Pediatric Dose
Not established; use in pediatric patients should be based on clinical judgment and careful monitoring.
Side Effects
Flushing, headache, gastrointestinal disturbances (nausea, diarrhea), jaw pain, hypotension, and infusion site reactions.
Contraindications & Precautions
Hypersensitivity to epoprostenol or any component of the formulation; patients with severe heart failure or those who cannot tolerate hypotension.
Important Warnings
Risk of rebound pulmonary hypertension upon abrupt discontinuation; caution in patients with bleeding disorders, renal impairment, or those on anticoagulant therapy; monitor for signs of infection at the infusion site.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.