About Epoprostenol
Class: | Prostacyclin analog
Use: | Treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and prolong survival
Adult dose: | Initial: 2 ng/kg/min IV continuous infusion; may be increased by 1-2 ng/kg/min every 15 minutes as tolerated, up to a maximum of 40 ng/kg/min
Pediatric dose: | Not established; use in pediatric patients should be based on clinical judgment and individual patient needs
Side effects: | Headache, flushing, hypotension, nausea, diarrhea, jaw p
Drug Class
Prostacyclin analog
Uses & Indications
Treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and prolong survival
Storage Requirements
Store in the refrigerator (2°C to 8°C or 36°F to 46°F); protect from light; once reconstituted, use immediately or store at room temperature for up to 24 hours
Manufacturer & Packaging
Manufacturer: GlaxoSmithKline Australia Pty Ltd, Australia
Package Size
1 Vial (Powder) + 2 Diluent Vial (50ml)
Price & Supplier
Price in UAE: AED 368.00
Dosage Information
Adult Dose
Initial: 2 ng/kg/min IV continuous infusion; may be increased by 1-2 ng/kg/min every 15 minutes as tolerated, up to a maximum of 40 ng/kg/min
Pediatric Dose
Not established; use in pediatric patients should be based on clinical judgment and individual patient needs
Side Effects
Headache, flushing, hypotension, nausea, diarrhea, jaw pain, and infusion site reactions
Contraindications & Precautions
Hypersensitivity to epoprostenol or any component of the formulation; severe pulmonary hemorrhage; and patients with certain cardiovascular conditions that may be exacerbated by vasodilation
Important Warnings
Risk of rebound pulmonary hypertension upon abrupt discontinuation; caution in patients with bleeding disorders or those on anticoagulant therapy; monitor for signs of infection at the infusion site and systemic effects of vasodilation
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.