About Estradiol Hemihydrate,Norethisterone Acetate
            
            Class: | Hormone Replacement Therapy (HRT) - Estrogen and Progestin Combination  
Use: | Treatment of menopausal symptoms such as hot flashes, vaginal dryness, and prevention of osteoporosis in postmenopausal women  
Adult dose: | 50 mcg/24 hrs (Estradiol) and 170 mcg/24 hrs (Norethisterone Acetate) applied as a transdermal patch, typically changed weekly  
Pediatric dose: | Not applicable; not recommended for use in pediatric populations  
Side effects: | Common side effects include nausea, hea
         
        
            
                
                
                    
                        Drug Class
                    
                    Hormone Replacement Therapy (HRT) - Estrogen and Progestin Combination
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of menopausal symptoms such as hot flashes, vaginal dryness, and prevention of osteoporosis in postmenopausal women
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct sunlight and moisture
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Theramex Ireland Limited, Ireland
                    
                    
                    Package Size
                    8's
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 98.11
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        50 mcg/24 hrs (Estradiol) and 170 mcg/24 hrs (Norethisterone Acetate) applied as a transdermal patch, typically changed weekly
                    
                    
                        Pediatric Dose
                    
                    
                        Not applicable; not recommended for use in pediatric populations
                    
                 
                
                
                    
                        Side Effects
                    
                    Common side effects include nausea, headache, breast tenderness, bloating, mood changes, and skin irritation at the application site
                 
             
         
        
        
            
                Contraindications & Precautions
            
            History of thromboembolic disorders, known or suspected breast cancer, estrogen-dependent tumors, undiagnosed vaginal bleeding, liver disease, and hypersensitivity to any components
         
        
        
            
                Important Warnings
            
            Increased risk of thromboembolic events, cardiovascular disease, and certain cancers; regular monitoring is recommended; not to be used in women with a history of stroke or heart attack
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.