About Estradiol Hemihydrate,Norethisterone Acetate
            
            Class: | Hormone Replacement Therapy (HRT) - Estrogen and Progestin Combination  
Use: | Treatment of menopausal symptoms such as hot flashes, night sweats, and vaginal dryness; prevention of osteoporosis in postmenopausal women; management of menstrual disorders.  
Adult dose: | Estradiol Hemihydrate 50 mcg/24 hrs and Norethisterone Acetate 170 mcg/24 hrs transdermal patches applied once weekly.  
Pediatric dose: | Not applicable; not indicated for use in pediatric populations.  
Side effects: 
         
        
            
                
                
                    
                        Drug Class
                    
                    Hormone Replacement Therapy (HRT) - Estrogen and Progestin Combination
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of menopausal symptoms such as hot flashes, night sweats, and vaginal dryness; prevention of osteoporosis in postmenopausal women; management of menstrual disorders.
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct sunlight and moisture.
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Theramex HQ UK LTD, United Kingdom
                    
                    
                    Package Size
                    8's (4 Patches (EVOREL 50) + 4 Patches (EVOREL CONTI))
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 114.24
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        Estradiol Hemihydrate 50 mcg/24 hrs and Norethisterone Acetate 170 mcg/24 hrs transdermal patches applied once weekly.
                    
                    
                        Pediatric Dose
                    
                    
                        Not applicable; not indicated for use in pediatric populations.
                    
                 
                
                
                    
                        Side Effects
                    
                    Common side effects include headache, nausea, breast tenderness, bloating, mood changes, and skin reactions at the application site.
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Known or suspected pregnancy, history of thromboembolic disorders, active liver disease, hormone-sensitive cancers, undiagnosed vaginal bleeding, and hypersensitivity to any components of the patch.
         
        
        
            
                Important Warnings
            
            Increased risk of thromboembolic events, cardiovascular disease, and certain cancers (e.g., breast and endometrial cancer) associated with long-term use; regular monitoring is recommended; not to be used in women with a history of stroke or heart attack.
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.