About Gilteritinib
Class: | Tyrosine kinase inhibitor
Use: | Treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation
Adult dose: | 120 mg orally once daily, taken continuously until disease progression or unacceptable toxicity
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Nausea, diarrhea, fatigue, edema, elevated liver enzymes, decreased appetite, and rash
Contraindications: | Hypersensitivity to gilteritinib
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F)
Manufacturer & Packaging
Manufacturer: Astellas Pharma Europe B.V., NETHERLANDS
Package Size
84's
Price & Supplier
Price in UAE: AED 85990.42
Dosage Information
Adult Dose
120 mg orally once daily, taken continuously until disease progression or unacceptable toxicity
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Nausea, diarrhea, fatigue, edema, elevated liver enzymes, decreased appetite, and rash
Contraindications & Precautions
Hypersensitivity to gilteritinib or any component of the formulation; severe hepatic impairment
Important Warnings
Risk of differentiation syndrome, hepatotoxicity, QT prolongation, and potential for embryo-fetal toxicity; monitor for signs of differentiation syndrome and liver function tests regularly
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.